Навыки: Разработка

Create and manipulate Seq, MutableSeq, and SeqRecord objects using Biopython. Use when creating sequences from strings,...

Calculate sequence statistics (N50, length distribution, GC content, summary reports) using Biopython. Use when analyzin...

Automated cell type annotation using reference-based methods including CellTypist, scPred, SingleR, and Azimuth for cons...

Read, write, create, and convert single-cell objects across AnnData (Python), Seurat (R), and SingleCellExperiment (R)....

Reconstruct cell lineage trees from CRISPR barcode tracing or mitochondrial mutations. Use when studying clonal dynamics...

Infer developmental trajectories and pseudotime from single-cell RNA-seq data using Monocle3, Slingshot, and scVelo for...

Preprocess small RNA sequencing data with adapter trimming and size selection optimized for miRNA, piRNA, and other smal...

Build spatial neighbor graphs for spatial transcriptomics data using Squidpy. Compute k-nearest neighbors, Delaunay tria...

Download sequencing data from NCBI SRA using the SRA toolkit. Use when downloading FASTQ files from SRA accessions, pref...

Build tissue and condition-specific metabolic models using GIMME, iMAT, and INIT algorithms with expression data constra...

Build genome-scale metabolic models from genome sequences using CarveMe and gapseq for automated reconstruction. Generat...

Analyze BCR repertoires for somatic hypermutation, clonal lineages, and B cell phylogenetics using the Immcantation fram...

Calculate immune repertoire diversity metrics, compare samples, and track clonal dynamics using VDJtools. Use when analy...

View, query, and interpret VCF/BCF variant files with bcftools and cyvcf2. Use when inspecting variants, extracting fiel...

Merge, concatenate, sort, intersect, and subset VCF files using bcftools. Use when combining variant files, comparing ca...

Generate variant statistics, sample concordance, and quality metrics using bcftools stats and gtcheck. Use when evaluati...

Create portable, standards-based bioinformatics pipelines with Common Workflow Language (CWL). Use when building workflo...

Reasons from thermodynamics, enzyme mechanisms, and binding energetics; designs orthogonal purification and assay readou...

Biome - Fast all-in-one toolchain for web projects (linter + formatter in Rust, 100x faster than ESLint)

Biome fast formatter and linter. Use for code quality.

Use when biome configuration including biome.json setup, schema versions, VCS integration, and project organization.

Creates and manages Biome GritQL custom lint rules to enforce coding patterns. Use when creating linter rules, enforcing...

Draft biomedical research manuscripts from research data. Use when user wants to write a research paper, has a project f...

研究 codex 使用 skill 生成 survey 這件事

Deep biomedical research orchestrator powered by the biomcp MCP server: clarifies the question, aligns research area pla...

Bootstraps a project-local biomcp MCP server runtime in .bioresearcher-runtime/: downloads portable Node.js 22 (if missi...

Downloads the past week's PubMed daily update XML.gz files from ftp.ncbi.nlm.nih.gov/pubmed/updatefiles/, streams-parses...

Searches New Zealand biosecurity public data from the Official NZ Pest Register, PIER import requirements metadata, data...

X/Twitter CLI for reading, searching, timelines, bookmarks, and posting via cookie auth.

Organize X/Twitter bookmark folders (collections) via GraphQL with Chrome cookie auth. Actions: list folders, list folde...

REQUIRED helper functions (never raw curl), workspace/repo_slug patterns, suggestion block syntax for code review

Bitcoin Core JSON-RPC interface: authentication (cookie, rpcauth), wallet vs node RPCs, common verbs (getblockchaininfo,...

Ark protocol: VTXOs (Virtual Transaction Outputs) batched off-chain with periodic on-chain settlement. ARKADE (Ark Labs)...

RGB protocol: client-side validated smart contracts on Bitcoin + Lightning. v0.12 consensus (zk-AluVM, issuers), the div...

Use when the user asks about Bitdefender GravityZone across every customer: which child companies have unmanaged, outdat...

Generate a bitstream and program a Xilinx FPGA over JTAG, or build an MCS image and burn it into SPI/BPI configuration f...

Bitwarden / Vaultwarden vault via the bw CLI — session, vault read/write, Send. Self-hosted, API key login then unlock f...

Source-cited draft: vat / gst for Benin (tax year 2025) — rates, thresholds and rules with primary-source citations. Unv...

帮助配置和启动本地开发服务器。当用户提到启动开发服务器、dev server、pnpm dev 时使用。

根据 TAPD 单据分析开发需求并生成方案。当用户需要开发 TAPD 需求/缺陷/任务时使用。

高频易错属性映射和避坑指南

蓝鲸前端知识库入口指南，包含规范、索引和工作流程

Initialize git-branchless in the current repository from the current branch

Record changes as a new commit in git-branchless workflow

Manage git-branchless commit stacks - view, navigate, and edit commits

Submit git-branchless stack as PRs - create branches and push to remote

Sync git-branchless stack with main branch - fetch, rebase, and handle merges

Undo git-branchless operations - recover from mistakes interactively